Dr Alison Bedford Russell – Overview of neonatal group B Streptococcal (GBS) disease

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Dr Alison Bedford Russell – Overview of neonatal group B Streptococcal (GBS) disease

Dr Alison Bedford Russell described how clinical presentations of group B Strep were different between early-onset and late-onset. For example, group B Strep meningitis was more common in late-onset than early-onset GBS infection, while pneumonia was the reverse. Focal infection (infection in a particular area of the body) was “very,very rare” when it came to early-onset, and less rare for late-onset, for example, septic arthritis. Overall, generalised sepsis was the most common presentation.

Dr Bedford Russell highlighted some of the difficulties of identifying early-onset GBS infection and also spoke of an increase in newborns presenting with “hypoxic ischemic encephalopathy” also referred to as HIE, a type of brain damage.

The number of deaths as a result of group B Strep infection were higher the more immature and the lower the birth weight of the baby. Around 7% of survivors of group B Strep infection had some disability.

“So, group B Strep is a bacterium that causes neonatal infection and indeed it is the
commonest cause of neonatal infection in the UK. Broadly speaking, infection is divided into early onset in the first 6 days of life or late onset, which is after that and before 90 days of life.”
Dr Alison Bedford Russell, Consultant Neonatologist, Medical Director Birmingham Women’s NHSFT

Click here to read the transcript

Click here to view the slides

By | 2017-01-11T18:39:44+00:00 June 15th, 2016|2015 GBS Conference|0 Comments